Research Scientist Job at ICON, Cambridge, MA

  • ICON
  • Cambridge, MA

Job Description

ICON seeks a Research Scientist in Cambridge, MA to develop and optimize multiplex immunofluorescence assays and image analysis workflows for clinical research studies. The role involves designing staining protocols, conducting tissue biomarker analyses, and collaborating across departments to support translational research and digital pathology initiatives.

Responsibilities

  • Develop and optimize quantitative image analysis workflows for multiplex immunofluorescence and spatial biology studies
  • Design, perform, and optimize mIF assays including tissue staining and multispectral imaging of FFPE samples
  • Collaborate with pathologists and bioinformaticians to translate findings into actionable biomarker insights
  • Maintain experimental records, prepare technical reports, and support assay validation activities
  • Support laboratory operations including instrument maintenance and coordination of digital pathology platform services

Requirements

  • B.S., M.S., or Ph.D. in life science or related discipline
  • Experience with multiplex immunofluorescence, digital pathology, or spatial biology
  • Proficiency in image analysis software such as Visiopharm, HALO, or QuPath
  • Experience with automated staining platforms like Leica Bond RX or Ventana Discovery Ultra
  • Experience with multispectral imaging systems such as Akoya PhenoImager or Zeiss
  • Strong analytical, problem-solving, and communication skills

Compensation: $68,616–$85,770 base

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